Exposure to polychlorinated compounds and cryptorchidism; A nested case-control study

Human Exposure to Endocrine-Disrupting Chemicals and Prenatal Risk Factors for Cryptorchidism and Hypospadias: A Nested Case–Control Study

BACKGROUND Exposure to xenoestrogens during pregnancy may disturb the development and function of male sexual organs. OBJECTIVE In this study we aimed to determine whether the combined effect of environmental estrogens measured as total effective xenoestrogen burden (TEXB) is a risk factor for male urogenital malformations. METHODS In a case-control study, nested in a mother-child cohort (n...

Occupational Exposure to pesticides and spontaneous abortion among female pistachio farmers: a case-control study

  Introduction: The majoritiy of abortion risk factors has been classified as environmental and vary from one place to another. This study aimed to explore the relationship between exposure to pesticides and spontaneous abortion among female pistachio farmers in Rafsanjan, Iran.   Materials and Methods: In this case-control study, 50 women with spontaneous abortion and 50 women w...

Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study

BACKGROUND Leakage of bacterial products across the gut barrier may play a role in liver diseases which often precede the development of liver cancer. However, human studies, particularly from prospective settings, are lacking. METHODS We used a case-control study design nested within a large prospective cohort to assess the association between circulating levels of anti-lipopolysaccharide (L...

A Case–Control Study of Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Cryptorchidism in Canadian Populations

BACKGROUND Polybrominated diphenyl ethers (PBDEs) are flame retardants found in North American household products during the past four decades. These chemicals leach out in dust as products age, exposing individuals daily through inhalation and ingestion. Animal studies suggest that PBDEs disrupt sex hormones and adversely affect development of the reproductive system. OBJECTIVES In the prese...

Case–Control Study, Nested